Glomerular filtration rate (GFR) has been the mainstay for diagnosing chronic kidney disease (CKD), and it provides a powerful tool for helping clinicians predict all-cause and cardiovascular mortality and kidney failure in patients. But what is the best equation for estimating an individual’s GFR? A new meta-analysis published in the Journal of the American Medical Association set out to answer this question.
Matsushita K, et al. Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate.. JAMA 2012; 307:1941–1951.