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Sam Kant and Duvuru Geetha

Kidney involvement is a major complication of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), manifesting clinically as rapid decline in glomerular filtration rate and histologically by Pauci-immune crescentic (Figure 1) and necrotizing (Figure 2) glomerulonephritis.

Cellular crescents

Extracapillary proliferation causes glomerular tuft deflation with disappearance of normal glomerular structure and occlusion of capillary lumina. This is better shown by Jones methenamine silver (JMS) staining (A) and periodic acid−Schiff (PAS) staining (B). (Image courtesy Paride Fenaroli)

Glomerular fibrinoid necrosis at Jones methenamine silver (JMS) staining

Silver staining hallmarks glomerular basement membranes (GBMs) and allows
Sam Kant and Matthew Sparks

The past year has been an arduous one. Amid the pandemic, we swiftly evolved in delivering our primary mission: patient care and education. The need for physical distancing did not culminate into any separation of trainees from education, with the majority of trainees agreeing that the educational endeavors of their programs were unaffected as a result of the pandemic (1). Local institutions and national organizations, led by prominent educators, continued to conduct conferences via innovative virtual platforms with high-quality content reaching audiences all over the globe. This edition of Kidney News is dedicated to trainees and

Sam Kant and C. John Sperati

SARS-CoV-2 infection, the causative agent of coronavirus disease 2019 (COVID-19), was declared a pandemic on March 11, 2020, with more than 1.4 million people afflicted by April 8, 2020, and more than 80,000 deaths (1). Physical distancing is the cornerstone of slowing disease transmission to mitigate an overwhelming demand for healthcare resources that exceeds capacity. This strategy was used as early as the fifth century BC (2), more recently during the 1918 influenza pandemic, and during the 2009 severe acute respiratory syndrome (SARS) and 2012 Middle East Respiratory Syndrome epidemics. Early physical distancing has in part

Matthew R. Sinclair, Tiffany Truong, and Sam Kant

For many years to come, just thinking of the year 2020 will put most of us into sympathetic overdrive. Coronavirus infectious disease 2019 (COVID-19) has dominated every part of our practice and continues to do so as we enter 2021. But if we track the arc of time, each tumultuous period has also spurred strides of innovation. Despite the odds, we have witnessed and continue to look forward to new landmark trials in nephrology that will have a lasting impact on our clinical practice. As our foray into the inaugural Fellows First column, we recap highlights of 2020 and anticipate

Tiffany Truong, Matthew R. Sinclair, and Sam Kant

Medical education, like medicine itself, has evolved over time—from the days of professional guilds and apprenticeships to the establishment of structured postgraduate residency training to duty-hours’ restrictions, changes in licensing exams, and the growth of innovative educational resources (1). As the design of medical training changes, so too does the type of physician it produces. After all, medical education is not simply the acquisition of knowledge or even of skills and experiences but a process of shaping and the metamorphosis of the learner.

In a field like medicine, interwoven as it is with the science and humanity of

Sam Kant MD and C John Sperati MD MHS

COVID-19 has necessitated a transformation in how medical education is delivered to trainees, presenting new opportunities, but also concerns for the adequacy of ongoing instruction. Education during the pandemic must “balance education with safety,” state Sam Kant, MD, and C. John Sperati, MD, in a Perspective to appear in the June Kidney News.  Here, we look at four areas that require the attention of educators and fellows in caring for patients with COVID-19. Sam Kant, MD, is a nephrology fellow at Johns Hopkins Hospital. C. John Sperati, MD, MHS, is associate professor of medicine and fellowship program director at Johns Hopkins Hospital.