“Exome sequencing in a cohort of over 3,000 patients demonstrated genetic causes of chronic kidney disease in about 10% of cases and genetic testing may aid in the treatment of these patients”.
The study, which was conducted with funds by the National Institutes of Health (NIH) and others, incorporated 3,307 patients over the age of 21, and 1,179 (35.6%) were of self-identified non-European ancestry. They “detected diagnostic variants in 307 of the 3,315 patients (9.3%), encompassing 66 different monogenic disorders. Of the disorders detected, 39 (59%) were found in only a single patient. Diagnostic variants were detected across all clinically defined categories, including congenital or cystic renal disease (127 of 531 patients [23.9%]) and nephropathy of unknown origin (48 of 281 patients [17.1%]). Of the 2,187 patients assessed, 34 (1.6%) had genetic findings for medically actionable disorders that, although unrelated to their nephropathy, would also lead to subspecialty referral and inform renal management”.
The American Academy of Pediatrics (AAP), in conjunction with the American Society of Pediatric Nephrology (ASPN), as part of the Choosing Wisely® campaign, recently “released a list of specific nephrology tests and procedures that are commonly ordered but not always necessary when treating children for kidney-related conditions”.
The Choosing Wisely recommendations include:
Choosing Wisely® is an initiative of the ABIM Foundation, which seeks to promote conversations between clinicians and patients in choosing care that is supported by evidence; does not duplicate other tests or procedures already received; is free from harm; and truly necessary.
With the current spread of COVID-19 (Coronavirus) and due to the American Society of Nephrology’s international outreach representing 21,000 members in 131 countries, the organization has responded to the developments in the following ways in order to share important information with the nephrology community:
In the future, ASN will continue to provide this level of coordination and education for the kidney community, including the possibility of more COVID-19 themed webinars and educational postings on the ASN website.
Today, the American Society of Nephrology (ASN) and the National Kidney Foundation (NKF) announced a new partnership with the US Department of Health and Human Services (HHS) to work on the new Public Awareness Initiative outlined in the Executive Order on Advancing American Kidney Health. The goals are to enhance awareness of kidney disease, educate clinical professionals and spur innovation by entities serving the kidney disease community.
Ensure kidney patients get the vascular access surgeries they need, and don’t delay kidney transplant surgeries.
These two directives formed the centerpiece of recent guidance from the Centers for Medicare and Medicaid Services (CMS), “Key Components for Continued COVID-19 Management for Dialysis Facilities,” released Monday, August 17, 2020.
Consumer Reports (CR) recently published an article, “Medical Algorithms Have a Race Problem,” which recognized the potential impact ASN and the National Kidney Foundation (NKF) could have through their joint task force to reassess the inclusion of race in diagnosing kidney disease.
The American Society of Nephrology (ASN), the European Renal Association – European Dialysis and Transplant Association (ERA-EDTA), and the International Society of Nephrology (ISN) released a joint statement today. The statement emphasizes the need for appropriate care for dialysis patients during the COVID-19 pandemic.
“Preliminary data have shown that about 20-30% of patients hospitalized with COVID-19 develop kidney failure, leading to a surge in requirement for dialysis. Yet regular dialysis services have been interrupted to prepare hospitals to provide care to COVID-19 patients.”
Terminology commonly used by physicians to describe kidney health may be distressing or too difficult to understand for patients with kidney diseases, according to a recent study published in CJASN. The study, “Patient and Caregiver Perspectives on Terms Used to Describe Kidney Health,” included 54 patients with chronic kidney disease (CKD) and 13 caregivers from the United States, United Kingdom, and Australia. Participants discussed various terms for kidney health, including kidney, renal, CKD, end-stage kidney disease, kidney failure, and descriptors for kidney function.
This podcast includes an interview with Suzanne Watnick, MD, FASN. Dr. Watnick is the Chief Medical Officer at Northwest Kidney Centers in Washington state and Professor of Medicine at the University of Washington. She discusses the steps her organization took to protect kidney patients and health care workers once the Coronavirus hit her state.