Key Research

The following articles cover important research advances in medicine, technology, treatment, and care delivery. Advancing research, development and innovation for kidney health, ASN supports initiatives and collaborations for improving dialysis, clinical trials, patient-centered products and therapies, and grants for studies and projects in nephrology.

 

ESTIMATED GLOMERULAR FILTRATION RATE RELATED RESEARCH

Nature Reviews Nephrology: Strengths and limitations of estimated and measured GFR

Kidney International: Characterization and implications of the initial estimated glomerular filtration rate ‘dip’ upon sodium-glucose cotransporter-2 inhibition with empagliflozin in the EMPA-REG OUTCOME trial

EClinicalMedicine: How unmeasured muscle mass affects estimated GFR and diagnostic inaccuracy

BMC Nehrology: Associations with kidney transplant survival and eGFR decline in children and young adults in the United Kingdom: a retrospective cohort study

CJASN: Kidney Disease, Race, and GFR Estimation

JASN: Reassessing the Inclusion of Race in Diagnosing Kidney Diseases: An Interim Report from the NKF-ASN Task Force

 

COVID-19 RELATED RESEARCH

New England Journal of Medicine: Safety, Immunogenicity, and Efficacy of the BNT162b2 Covid-19 Vaccine in Adolescents

Nephron: COVID-19 Attacks the Kidney: Ultrastructural Evidence for the Presence of Virus in the Glomerular Epithelium

Kidney International: COVID-19 infection in kidney transplant recipients

JASN: Comparative Analysis of SARS-CoV-2 Reproduction Rates in the Dialysis and General Populations

CJASN: Proteinuria and Clinical Outcomes in Hospitalized COVID-19 Patients

Kidney360: Machine Learning for Prediction of Patients on Hemodialysis with an Undetected SARS-CoV-2 Infection

JASN: Kinetics of Anti–SARS-CoV-2 IgG Antibodies in Hemodialysis Patients Six Months after Infection

 

CHRONIC KIDNEY DISEASE RELATED RESEARCH

Nature Reviews Nephrology: Lipoproteins and fatty acids in chronic kidney disease: molecular and metabolic alterations

BMC Nephrology: Decision-making process in the pre-dialysis CKD patients: do anxiety, stress and depression matter?

Kidney International: The prevalence of chronic kidney disease in Iceland according to KDIGO criteria and age-adapted estimated glomerular filtration rate thresholds

CJASN: Low Serum Bicarbonate and CKD Progression in Children

JASN: Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease

Kidney360: Podocyte Lipotoxicity in Chronic Kidney Disease

 

GLOMERULAR DISEASES RELATED RESEARCH

Kidney International: Identifying geospatial “hot spots” of glomerular diseases: opportunities and challenges

Nephron: De novo Glomerular Disease and the Significance of Electron Microscopy in Renal Transplantation

BMC Nephrology: Biobanking for glomerular diseases: a study design and protocol for KOrea Renal biobank NEtwoRk System TOward NExt-generation analysis (KORNERSTONE)

JASN: Current Methodological Challenges of Single-Cell and Single-Nucleus RNA-Sequencing in Glomerular Diseases

Kidney360: Glomerular Diseases in Patients with Diabetes Mellitus: An Underappreciated Epidemic

CJASN: Glucocorticoids in the Treatment of Glomerular Diseases

 

ACUTE KIDNEY INJURY RELATED RESEARCH

Kidney360: AKI in a Patient with Pyuria and an Alkaline Urine

CJASN: AKI in Patients Receiving Immune Checkpoint Inhibitors

JAMA: Recommendations on Acute Kidney Injury Biomarkers From the Acute Disease Quality Initiative Consensus Conference

BMC Nephrology: Acute kidney injury and cardiac surgery: impact of fluid balance on AKI classification and prognosis

American Journal of Kidney Diseases: Timing of Recovery From Moderate to Severe AKI and the Risk for Future Loss of Kidney Function

JASN: Racial Differences in AKI Incidence Following Percutaneous Coronary Intervention

CJASN: AKI Associated with Acute Pancreatitis