Novel Nephrology

Novel Nephrology

the American Society of Diagnostic and Interventional Nephrology (ASDIN) is dedicated to enhancing the quality of care that patients receive related to vascular access, peritoneal dialysis access, and ultrasonography. Established in 2000, the mission of ASDIN is to promote the appropriate application of new and existing procedures in order to improve the care of patients with kidney disease. Membership includes physicians, nurses, technicians, and administrators—all with interest in this specialized field.

acute kidney injury (AKI) often presents formidable risks to patients in critical care units, particularly those with associated multiorgan failure. Such patients are very likely to die in spite of the best efforts of providers. With this in mind, aggressive management of AKI using hemofiltration and/or dialytic therapy has evolved. Systems appropriate for use in pediatric patients are limited today.

recent advances in molecular diagnostics are making inroads in how we manage patients with kidney-related disorders. Techniques such as nucleic acid amplification and detection, genomic analysis, proteomics, and metabolomics have enabled development of several molecular diagnostic assays. These developments, in turn, affect the practice of various aspects of nephrology, such as management of acute kidney injury, chronic kidney disease (CKD) and its complications, as well as transplant nephrology.

Since its introduction in the early 1960s, ultrasonography has become an essential part of the workup and management of patients with kidney disease owing to its safety, low cost, and the ease of visualizing the kidneys, bladder, and blood vessels. Given ultrasonography’s simplicity and utility, it is curious it is not routinely performed by many nephrologists, considering that ultrasonography has become a standard procedure for many other specialists and subspecialists.

a mbulatory blood pressure monitoring (ABPM) is a noninvasive, automated method for measurement of brachial artery blood pressure (BP) in a nonclinical setting. The two major benefits of ABPM are that the measurements reflect the diurnal pattern of BP of the individual and that data are obtained outside the clinic or hospital setting. There are excellent reviews on use of ABPM in children and adults (13). This article will cover the basics of ABPM—methodology, applications, and indications.

Merriam-Webster’s online dictionary defines the adjective “novel” as

  1. new and not resembling something formerly known or used, or
  2. original or striking, especially in conception or style.

Both definitions apply to the topics covered in this special section, which include noninvasive or minimally invasive diagnostic techniques as well as new interventions to treat disease, all of which can be performed by nephrologists.