For patients with diabetes—including but not limited to low-income patients—switching to high-deductible health plan (HDHPs) leads to major increases in emergency department visits for preventable acute diabetic complications, reports a study in JAMA Internal Medicine.

Among living kidney donors, the long-term risk of ESRD is close to doubled for those who are obese, reports a study in Kidney International.

The study included data on 119,769 living kidney donors, linked to Centers for Medicare & Medicaid Services data to determine ESRD status. There were 20,588 obese donors, body mass index (BMI) 30 kg/m2 or higher; and 58,004 nonobese donors. (The remaining 41,177 donors had missing data on BMI.) Postdonation risk of ESRD was compared between groups, with adjustment for potential confounders.

A growing understanding of the health and psychosocial risks associated with being a living kidney donor is helping drive innovations that will improve the informed consent process, according to recent research.

More than 1 billion people worldwide now have hypertension, with the highest levels now seen in low-income countries in south Asia and sub-Saharan Africa, according to a report in The Lancet.

The NCD Risk Factor Collaboration analyzed pooled data from 1479 studies that had measured blood pressure in 19.1 million adults. The researchers analyzed trends in mean systolic and diastolic blood pressure from 1975 to 2015, as well as the prevalence of raised blood pressure (140/90 mm Hg or higher) in 200 countries.

Among patients initiating dialysis, mortality is higher for those with a primary indication of volume overload or hypertension, suggests a study in the American Journal of Kidney Diseases.

In a diverse urban population, low dietary quality is associated with an increased risk of declining kidney function among adults with hypertension, reports a study in the Journal of Renal Nutrition.

The study included data on 1534 participants in the “Healthy Aging in Neighborhoods of Diversity across the Life Span” (HANDLS) study: African Americans and whites, aged 30 to 64 years, with a baseline estimated glomerular filtration rate (eGFR) of 60 mL/min/1.73 m2 or higher. Mean age was 48 years; 59% of participants were African American.

Acute kidney injury (AKI) is strongly associated with an increased risk of unplanned hospital readmissions—especially for acute pulmonary edema, according to a study in BMC Nephrology.

The researchers analyzed Scottish population-based data on 16,453 patients who were hospitalized and survived to discharge in 2003. Of these, 2623 patients had AKI, based on KDIGO criteria. AKI and other candidate predictors were analyzed as risk factors for unplanned readmission or death within 90 days.

Screening for elevated albuminuria and hypertension may identify a group of patients at increased risk of faster decline in kidney function, reports a study in Nephrology Dialysis Transplantation.


Acute kidney injury (AKI), often severe, develops in more than one-fourth of children admitted to pediatric intensive care units, reports a study in The New England Journal of Medicine.

The quality of primary care management of diabetes is lower for physicians with higher-volume practices, but higher for those with greater diabetes-specific volume, reports a study in Annals of Internal Medicine.