Findings

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Lack of interest in the subject is the most common reason why medical students and residents say they wouldn’t want to pursue a career in nephrology, reports a survey study in the open-access journal BMC Nephrology.

Among patients who successfully lost weight in the Diabetes Prevention Program (DPP) study, long-term maintenance of weight loss is better for those initially assigned to metformin compared to a lifestyle intervention, reports a study in Annals of Internal Medicine.

In children with end stage kidney disease (ESKD), there is no specific level of renal function at which dialysis initiation leads to improved patient outcomes, concludes a registry study in Nephrology Dialysis Transplantation.

Among patients with chronic kidney disease (CKD), baseline biomarkers of tubule cell function are independent predictors of the later development of acute kidney injury (AKI), reports a study in Kidney International.

Combination therapies including amlodipine improve blood pressure (BP) control in sub-Saharan African patients with hypertension, concludes a trial in The New England Journal of Medicine.

Exposure to high doses of nonsteroidal anti-inflammatory drugs (NSAIDs) shows a modest but significant association with kidney disease in a military population, reports a study in the open-access journal JAMA Network Open.

The retrospective analysis included data on more than 764,000 US Army soldiers on active duty from 2011 through 2014. Eighty-six percent of participants were men; median age was 27 years. Dispensing and dose of prescription NSAIDs were evaluated for association with incident diagnoses of acute kidney injury (AKI) and chronic kidney disease (CKD).

The risks of cardiovascular events and mortality are lowest with the combination of moderate sodium intake and higher potassium intake, concludes an international prospective cohort study in the British Medical Journal.

The “Prospective Urban Rural Epidemiology” (PURE) study enrolled more than 103,000 adults, aged 35 to 70, from 628 urban and rural communities in low-, middle-, and high-income countries. Twenty-four-hour urinary sodium and potassium excretion were estimated (as surrogates for intake) from morning fasting urine samples.

A new serum test of calcification propensity provides useful information on the severity and progression of coronary artery calcification (CAC) in patients with chronic kidney disease, reports the American Journal of Kidney Diseases.

Exposure to high doses of nonsteroidal anti-inflammatory drugs (NSAIDs) shows a modest but significant association with kidney disease in a military population, reports a study in the open-access journal JAMA Network Open.

The retrospective analysis included data on more than 764,000 US Army soldiers on active duty from 2011 through 2014. Eighty-six percent of participants were men; median age was 27 years. Dispensing and dose of prescription NSAIDs were evaluated for association with incident diagnoses of acute kidney injury (AKI) and chronic kidney disease (CKD).

Automated office blood pressure (AOBP) readings are more accurate than office measurements and should be the “preferred method” for recording BP in clinical practice, concludes a meta-analysis in JAMA Internal Medicine.

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