Young Investigator Recognized for Fibrogenesis Research

Jeremy S. Duffield


The ASN will present its Young Investigator Award to Jeremy S. Duffield, MD, PhD, for his groundbreaking research on fibrogenesis. He will describe his recent findings in an address, “New Insights into Mechanisms and Consequences of Fibrogenesis: An Avenue to Novel Therapeutics for Kidney Disease.”

Dr. Duffield is associate professor of medicine at the University of Washington Medical School in Seattle, where he also directs the inflammation research laboratory at the Kidney Research Institute.

An established National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) investigator, he heads a laboratory focused on the role of the innate immune response cells called monocytes in injury and repair and on the role of the mesenchymal cells known as pericytes and fibroblasts in microvascular remodeling and fibrosis. This research has led to several candidate therapeutics now being tested in clinical trials.

Dr. Duffield received young investigator awards from the British Renal Association, the U.K.’s Medical Research Society, and the NIDDK; a Gottschalk Award from the American Society of Nephrology; and a challenge grant from the National Institutes of Health.

In 2011 he was elected a member of the American Society for Clinical Investigation. He also serves on scientific study sections at the NIDDK and the National Heart, Lung, and Blood Institute. He is on the scientific advisory boards of Promedior and Regulus Therapeutics, companies dedicated to the development of anti-fibrotic therapies.

He also practices nephrology at the University of Washington Medical Center with special interests in systemic lupus erythematosus, systemic vasculitis, and pregnancy-related kidney disorders.

Dr. Duffield studied medicine and developmental biology at Oxford University and obtained a doctorate in medicine and immunology at Edinburgh University in the U.K. He moved to the United States in 2003 and worked as assistant professor of medicine at Harvard medical school until 2010.

October-November 2013 (Vol. 5, Number 10 & 11)