Cover Stories

Acute kidney injury (AKI) is a global problem affecting patients all over the world—but it’s not the same everywhere. A prospective, worldwide comparison of AKI patients revealed significant differences in patient characteristics, treatment, and outcomes between developed and emerging countries, according to a study in the Clinical Journal of the American Society of Nephrology.


The incidence of stroke is estimated to be 2- to 7-times higher in patients with chronic kidney disease (CKD) than in individuals with normal kidney function, depending on age and the population studied. Also, patients with CKD have a higher risk of developing dementia than the general population.

Just over half of adults in the United States—including nearly two-thirds of African Americans—have health conditions that would preclude their becoming living kidney donors, according to a study presented at Kidney Week 2014.

Higher levels of muscle mass contribute to higher quality of life for dialysis patients and could partially explain the “obesity paradox,” in which dialysis patients with a higher body mass index (BMI) have greater survival times than those with a lower BMI, according to a new study. The longer survival of heavier patients has long confused researchers because obese dialysis patients generally have lower levels of physical function, and better physical function is also associated with better survival as well as better quality of life.

The Centers for Medicare & Medicaid Services (CMS) has announced a new—and likely its last—request for applications (RFA) for the ESRD Seamless Care Organizations (ESCOs).


Numerous studies have shown that maternal health and the uterine environment may affect certain aspects of an offspring’s well-being. Kidney health appears to be no exception.

Even small amounts of physical activity may slow kidney function decline in patients with chronic kidney disease (CKD), according to two studies recently published in the Journal of the American Society of Nephrology. The studies, from two different teams at the same institution, suggest that exercise may have powerful effects on kidney health, such as reducing the risk of developing kidney stones in the general population.


A major frustration for any physician is watching a noncompliant patient deteriorate, particularly one with a long-term condition like kidney disease. So the turnaround New York City’s Mount Sinai achieved through an accountable-care-style program with a 53-year-old patient on dialysis with poorly controlled diabetes and heart problems provides a hopeful example.