Cover Stories

A new approach aimed at turning one altruistic kidney donation into a never-ending chain could be the next step in increasing the number of transplanted kidneys, a recent report in the New England Journal of Medicine proposes. The new system is called a nonsimultaneous, extended, altruistic donor (NEAD) chain.

With panoramic views of both the city and sparkling San Diego Bay, the convention center is a short walk from the vibrant Gaslamp Quarter, a hub for dining, shopping, and entertainment.


Advanced care planning and end-of-life discussions are never easy, but for nephrologists they are a necessary part of caring for ESRD patients. As the general population ages and the incidence of CKD continues to climb, more researchers and clinicians are reassessing the role of palliative care in ESRD.

Chronic hepatitis C virus (HCV) infection raises the risk for chronic kidney disease (CKD) in people infected with human immunodeficiency virus (HIV). Clearing the HCV infection appears to reverse this effect, researchers have found.


Recent findings may help explain the calcium paradox—the relationship between osteoporosis and atherosclerosis—that plays a large role in aging and is a particular concern in those with chronic kidney disease (CKD).

Enhanced laboratory-based treatment prompts may improve primary care physicians’ prescribing habits in some situations, but that does not seem to be the case when it comes to prescribing recommended medications for elderly patients with chronic kidney disease (CKD). That was the conclusion of a study in the April Clinical Journal of the American Society of Nephrology.


The American Society of Nephrology recently joined forces with other leading medical organizations in a campaign to identify and reduce wasteful health care spending while improving patient outcomes at the same time.

For 20 years, the use of erythropoiesis-stimulating agents (ESAs) has improved the health and quality of life for patients with chronic kidney disease (CKD) while reducing the need for blood transfusions. By replacing erythropoietin, a protein made by the kidneys but deficient when the kidneys fail, ESAs help correct the anemia of CKD by stimulating the bone marrow to produce more red blood cells.

Two curious youths with urine flasks attend a group of physicians. Sparking curiosity about the kidneys could help spur young people to become nephrologists. See special section, p. 11.


Johannes de Ketham, Fasciculus Medicinae. In comincia el dignissimo Fasciculo de Medicina in Volgare. Venice: Giovanni & Gregorio di Gregorii, 5 Feb. 1493/4.