Surgery Is Better than Bisphosphonates for Preventing Fractures in Patients with Hyperparathyroidism

Among 6272 people diagnosed with hyperparathyroidism between 1995 and 2010, there were 56 hip fractures per 1000 people after 10 years among those not treated for hyperparathyroidism. Among those who had parathyroid surgery, there were just 20 fractures per 1000 people. Surprisingly, the hip fracture rate was highest among those taking bisphosphonates, at 86 fractures per 1000 patients. Similar results were seen for bone fractures of all types. People taking medications had a higher fracture risk even though X-rays showed that they had similar gains in bone density as surgery patients, according to the Annals of Internal Medicine study.

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Among 6272 people diagnosed with hyperparathyroidism between 1995 and 2010, there were 56 hip fractures per 1000 people after 10 years among those not treated for hyperparathyroidism. Among those who had parathyroid surgery, there were just 20 fractures per 1000 people. Surprisingly, the hip fracture rate was highest among those taking bisphosphonates, at 86 fractures per 1000 patients. Similar results were seen for bone fractures of all types. People taking medications had a higher fracture risk even though X-rays showed that they had similar gains in bone density as surgery patients, according to the Annals of Internal Medicine study.

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