Recipients of Kidney Retransplantation Face Increased Risk of Renal Cell Carcinoma

In a study that examined cancer risk in recipients of kidney retransplantation, investigators found that overall cancer risk did not differ in retransplants compared with primary recipients.; hHowever, renal cell carcinoma occurred in excess among retransplants, with an adjusted incidence rate ratio of 2.03. The researchers noted that this increased risk may be explained by the presence of acquired cystic kidney disease, which is more likely to develop with additional time with kidney disease and time spent on dialysis waiting for retransplantation. The Clinical Transplantation study included 109,224 primary recipients and 6,621 retransplants.

 

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In a study that examined cancer risk in recipients of kidney retransplantation, investigators found that overall cancer risk did not differ in retransplants compared with primary recipients.; hHowever, renal cell carcinoma occurred in excess among retransplants, with an adjusted incidence rate ratio of 2.03. The researchers noted that this increased risk may be explained by the presence of acquired cystic kidney disease, which is more likely to develop with additional time with kidney disease and time spent on dialysis waiting for retransplantation. The Clinical Transplantation study included 109,224 primary recipients and 6,621 retransplants.