Recent JASN study: Hemodialysis linked with decline in cognitive function

By ASN Staff

In a recent study published by the Journal of the American Society of Nephrology (JASN), set out to examine the “immediate and longer-term effects of hemodialysis on cerebral circulation, cerebral structure, and cognitive function as they are currently poorly understood.

97 hemodialysis patients, with a median age of 59 years, were included in the study and the tests occurred over a 12-month period. During which transcranial Doppler ultrasounds were used to “measure cerebral arterial mean flow velocity (MFV) throughout dialysis, as well as cognitive scores, and MRI imaging.

The findings concluded that hemodialysis is capable of inducing transient cerebral stunning, thereby offering one mechanism of cerebral injury in end-stage renal disease (ESRD). “Progressive cerebrovascular disease occurred in those continuing dialysis, but not in transplanted patients”. In fact, “cognitive function and cerebral diffusion improved after transplant”.

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In a recent study published by the Journal of the American Society of Nephrology (JASN), set out to examine the “immediate and longer-term effects of hemodialysis on cerebral circulation, cerebral structure, and cognitive function as they are currently poorly understood.

97 hemodialysis patients, with a median age of 59 years, were included in the study and the tests occurred over a 12-month period. During which transcranial Doppler ultrasounds were used to “measure cerebral arterial mean flow velocity (MFV) throughout dialysis, as well as cognitive scores, and MRI imaging.

The findings concluded that hemodialysis is capable of inducing transient cerebral stunning, thereby offering one mechanism of cerebral injury in end-stage renal disease (ESRD). “Progressive cerebrovascular disease occurred in those continuing dialysis, but not in transplanted patients”. In fact, “cognitive function and cerebral diffusion improved after transplant”.

Date:
Thursday, December 27, 2018