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Fluid management is an area ripe for innovation that has a significant impact on the quality of life of people with kidney failure. The Kidney Health Initiative (KHI) recently released a supplement to its Technology Roadmap for Innovative Approaches to Renal Replacement Therapy entitled Fostering Innovation in Fluid Management . This report provides guidance to spur innovation in fluid management devices and techniques. Similar to the original roadmap, this new report is built around patient preferences and provides details on design requirements, functional areas, and development timelines.