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Karen Blum

WASHINGTON, DC -- Biopsies remain the gold standard for diagnosing post-transplant kidney disease but they are imperfect, a speaker said here during Kidney Week 2019. Emerging biomarkers may provide a complement to helping nephrologists diagnose and manage disease. The session entitled, "Needle Phobia: Kidney Transplant Biopsy Alternatives" , included four speakers on the topic.

ASN Staff

NephSAP Volume 18, Number 4, September 2019

Chronic Kidney Disease and Progression

CKD burden continue to remain high in the United States and Medicare spending for all beneficiaries who had CKD exceeded $79 billion in 2016. The 2019 Chronic Kidney Disease issue of NephSAP guides readers through the latest advances in clinical research for this common and costly disease. This issue of NephSAP provides a background of the clinical research published during the years 2017 and 2018, and covers several major areas of CKD research: epidemiology, biomarkers relevant to incidence and progression, genetic variants, cardiovascular disease, weight loss interventions, and novel tools to improve CKD care measures. There have been exciting developments in our understanding of the pathogenesis and treatment options for diabetic kidney disease in the recent years. Several relevant clinical trials that demonstrated improvements in outcomes for those with diabetic kidney disease  have been highlighted in this issue. Along with it, several novel risk factors for progression of kidney disease have also been discussed. Cardiovascular disease remains the principal cause of death for adults with CKD. This NephSAP outlines advances in management of atrial fibrillation and the use of device therapy in CKD. The epidemiology and conseqeuences of pulmonary hypertension, peripheral artery disease and congnitive function in those with CKD are also discussed. Clinical practitioners will also be provided with insight into topics ranging from management of obesity along with understanding about novel methodology and tools that have been tested to help improve CKD care delivery. Finally, readers can also test their knowledge with a series of 30 questions.

 

ASN Staff

Name: Tomokazu Souma, MD, PhD

Institution: Duke University

Grant: Carl W. Gottschalk Research Scholar Grant (2019)

Project Title: Harnessing Antioxidative Stress Pathways in Renal Epithelial Progenitors To Prevent AKI-to-CKD Transition

 

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ASN Staff

Name: Tengis S. Pavlov, PhD

Institution: Henry Ford Health System

Grant: Carl W. Gottschalk Research Scholar Grant (2019)

Project Title: Mechanism and Role of ATP Release in Polycystic Kidney Diseases

 

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ASN Staff

Name: Sarah Panzer, MD

Institution: University of Wisconsin Madison

Grant: John Merrill Grant in Transplantation (2019)

Project Title: Impact of B Cell Survival Cytokines on Transplant Glomerulopathy



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ASN Staff

Name: Sagar U. Nigwekar, MD, MMSc

Institution: Massachusetts General Hospital

Grant: Carl W. Gottschalk Research Scholar Grant (2019)

Project Title: Novel Determinants of Calcific Uremic Arteriolopathy

 

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ASN Staff

Name: Naoka Murakami, MD PhD

Institution: Brigham and Women's Hospital

Grant: Carl W. Gottschalk Research Scholar Grant (2019)

Project Title: Roles of Immune Checkpoint Signaling in Autoimmune Kidney Diseases

 

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ASN Staff

Name: Louise Evans, PhD

Institution: University of Minnesota

Grant: Carl W. Gottschalk Research Scholar Grant (2019)

Project Title: Pathological Role of T-cells in Salt-Sensitive Hypertension.

 

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ASN Staff

Name: Dylan Dodd, MD, PhD

Institution: Stanford University

Grant: OHF-ASN Foundation for Kidney Research Grant (2019)

Project Title: Gut Microbiota Modulation of Oxalate

 

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ASN Staff

Name: Subhashini Bolisetty, PhD          

Institution: University of Alabama at Birmingham

Grant: Carl W. Gottschalk Research Scholar Grant (2019)

Project Title: Targeting Ferritin in Sepsis-Associated Acute Kidney Injury



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