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Hepatitis C virus (HCV) affects approximately 4 million Americans, and can trigger, share risk factors for, or result from CKD. Besides causing glomerulonephritis, HCV is associated with diabetes, a CKD precursor. End stage renal disease (ESRD) is a risk factor for HCV, transmitted via transfusions or transplantation in the era preceding its identification. The estimated HCV prevalence among U.S. CKD patients is 10 percent, several-fold higher than the general population, and is presumed to increase with CKD stage, with demographic variation. While acute infection is often subclinical, chronic HCV infection develops in most patients, leading to cirrhosis, hepatocellular carcinoma, and
Glomerulonephritis (GN)—including both primary and secondary variants in aggregate—remains one of the most common types of kidney disease that progresses to end stage renal disease (ESRD). However, this fact alone seriously underestimates the extent of the problem associated with GN. Many cases of the disease begin early in life and can have a devastating effect both on the individual and their families. The disease process is often slowly progressive and therefore its devastating impact on the individual’s physical growth, educational opportunities, quality of life, and eventual societal productivity is rarely taken into account when assessing the impact of these disorders.
The authors of the Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline for acute kidney injury (
My answer to the first question is that the guideline is for physicians to aid them in the treatment of patients—but which patients and, for that matter, which physicians? These are fair points, and the KDIGO AKI Work Group spent some time debating them. In the end we decided that the guideline was meant for “front-line” physicians, not just for subspecialists. Indeed,
Improving access to, and retrieval of, your research articles is the surest way to enhance their impact. Repetition, consistency, and an awareness of the intended audience form the basis of most of the following strategies in areas related to preparation for publication, dissemination of content, and keeping track of your research.
The
As awareness of kidney disease within the general population increases, so will nephrologists’ need for a safe, efficient, and Health Insurance Portability and Accountability Act (HIPAA)–compliant system for securely managing incoming
Suffering from information overload is a frustrating and all-too-common condition today. If it isn’t hard enough to clear your overflowing email inbox, there’s the stress of staying on top of the blossoming number of journals and medical blogs in your field, papers uncovered through regular PubMed or Medline searches, not to mention the pressure of keeping up-to-date with the latest must-use social media tools. And yet, a small number of people seem to stay afloat while the vast majority of us are drowning in information. What’s their secret?
Every year, the Science Online conference in North Carolina brings together some
Twitter has taken the world by storm. No one could have predicted that just 6 years after its inception Twitter would have 300 million users generating 300 million messages every day (
Twitter is an open forum for sharing real-time information through “tweets.” A tweet is a short message of 140 characters or less that can convey absolutely anything to your “followers” (people who subscribe to your “feed” of tweets). And
Understanding the true value of a scholar’s research and output is no small feat. Although it’s fairly straightforward to track the number of publications or total dollar amount of awarded funding, it can be a greater challenge to assess the reach of scholarly efforts and determine how others are utilizing the research results. Metrics for assessing research performance, quality, and impact cover a wide range of the scholarly ecosystem and are used for a variety of purposes: individual career planning, promotion, and tenure; benchmarking to track group or institutional performance; marketing and strategic planning purposes; and reporting research outcomes to
The incidence of ESRD is increasing, with a current prevalence of over half a million patients in the United States. Most ESRD patients are treated with hemodialysis (HD) and the number of patients receiving peritoneal dialysis (PD) has steadily declined over the past several decades. According to the U.S. Renal Data System 2011 annual report, approximately 7 percent of patients were being treated with PD at the end of 2009, reflecting gross underuse of this form of therapy (
The growth in the number of
