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Norine W. Chan and Lisa M. McElroy

Structural racism is a root cause of health inequities. The term structural racism refers to differential access by racial group to opportunities, resources, and societal well-being and is mediated through complex health care systems (1). To undergo kidney transplant, patients must navigate a multistep, conditional process that requires multiple health system and clinician interactions. This process exerts a differential burden on patients from marginalized groups. Studies in recent decades have demonstrated that racial minority groups experience lower rates of kidney transplant listing and transplant compared with patients of White race (2, 3). Patients of

Tracy Hampton

Two recent studies published in CJASN address different aspects of the COVID-19 pandemic in adults with advanced kidney diseases: one examines whether prior COVID-19 vaccination affected the outcomes of individuals on dialysis who became infected with SARS-CoV-2 (1), and the other assesses the pandemic's impact on treatment decision-making for older patients with chronic kidney disease (CKD) (2).

People with CKD or other severe chronic medical conditions are at higher risk for more serious COVID-19 illness, and patients with kidney failure who rely on in-center hemodialysis face an elevated risk of becoming exposed to the

A. Cozette Killian, Paige M. Porrett, Jayme E. Locke, and Vineeta Kumar

In 1964, the first kidney xenotransplant from a chimpanzee to human was performed successfully (1). Although the recipient survived 9 months, subsequent animal-to-human transplants were limited by immunologic barriers and the need for a sustainable organ source (2). Pigs soon became the ideal organ source because they produce large litters and mature rapidly, and availability is virtually unlimited (2, 3). Pigs have organs comparable in size and function with humans and lower risk of zoonoses, and their hormones and tissues are already used, suggesting positive public opinion (2, 3

Susan E. Quaggin

As we approach the middle of the year, those of us who live in locations with long, harsh winters are basking in the remainder of spring and its glorious diversity: multi-colored blossoms and greenery, rain, sun, and ever-changing temperatures. During my #850challenge (1) run this morning, I was struck how fitting it is that the joy of spring and oncoming summer coincides with Pride month—a month filled with opportunities to celebrate diversity and all the power and growth it brings to the kidney community.

Pride month is celebrated annually in June in the United States, culminating in festive

Mark A. Perazella and Mitchell H. Rosner

Over the past 10 to 20 years, there has been a revolution in the care of patients with cancer. In addition to classic chemotherapy agents, anti-cancer agents now include targeted therapies and immunotherapies, which harness the power of the immune system. These new therapies have transformed cancer into a chronic disease for many patients. Importantly, acute and chronic kidney diseases, electrolyte and acid-base disorders, and hypertension have become highly prevalent complications in this group of patients. This is particularly true for those with liver cancer, multiple myeloma, renal cell carcinoma, leukemias and lymphomas, and cancer patients treated with potentially nephrotoxic

Evan Xu and Ziyad Al-Aly

Beyond its acute effects, it is now compellingly clear that infection with SARS-CoV-2 leads to serious long-term health consequences—referred to as long COVID. Of particular concern is the increased risk of cardiometabolic disease, including kidney diseases, diabetes, and cardiovascular disease (Figure 1).

Cardiometabolic consequences of long COVID

In the first large-scale, high-dimensional characterization of the post-acute sequelae of COVID-19, we showed that people who survive the acute phase of COVID-19 have increased risk of post-acute sequelae involving pulmonary and a wide array of extrapulmonary disorders (1).

Further work from our team revealed that people

This is an abridged version of ASN's Statement on Climate Change, which can be viewed in its entirety online at

The American Society of Nephrology (ASN) calls on kidney health professionals to take action to address the impact of climate change on the 850 million people—including more than 37 million Americans—living with kidney diseases across the world who are uniquely vulnerable to the effects of climate change.

Climate change—defined by the United Nations Framework Convention on Climate Change as “a change of climate which is attributed directly or indirectly to human activity that alters the

Drinking at least two cups of coffee per day has a protective effect against acute kidney injury (AKI), reports a study in Kidney International Reports.

The analysis included 14,207 adults, aged 45 to 64 years, from the population-based Atherosclerosis Risk in Communities (ARIC) study. Coffee consumption was assessed at a single study visit using a semiquantitative food-frequency questionnaire and was evaluated for association with incident AKI.

Of the participants, 27% never drank coffee, 14% drank less than one cup per day, 19% drank one cup per day, 23% drank two or three cups per day, and 17% drank

Adam Weinstein and Eileen Brewer

Health care providers eagerly anticipate the Centers for Medicare & Medicaid Services (CMS) updates to the physician fee schedule (PFS) in the Federal Register each fall. The PFS, which assigns relative value units (RVUs) to Current Procedural Terminology (CPT) codes, is CMS's price list for physician services. The published CPT values result from thousands of hours of work by specialty society representatives (called advisors) and the 32 members of the American Medical Association (AMA)/Specialty Society Relative Value Scale Update Committee (RUC) (1).

Per AMA bylaws, specialty societies that meet requirements for representation in the AMA House

Detective Nephron, world-renowned for his expert analytic skills, trains budding physician-detectives in the diagnosis and treatment of kidney diseases. Mackenzie Ula Densa, a budding nephrologist, plans to present a new case to the master consultant.

Nephron It's been a while, Mac. What do you have for me?

Mac I have a 67-year-old man with a serum sodium (Na) of 120 mEq/L.

Nephron (excited) Whoa! Finally…electrolytes stuff!

Mac Trust me, you are going to love this one. You are like a child when it comes to hyponatremia.

Nephron Did you know that hyponatremia is