Diabetes & Metabolism

ASN Data Bytes: 2016 Survey Finds American Physicians in a Sour Mood

ASN Data Science Officer Kurtis Pivert takes a look at a new survey of American physicians: regulatory and administrative pressures are taking a big bite out of the joy of practicing medicine.

Building the Future: ASN Expands TREKS to Chicago

TREKS students learn why the best and brightest get hooked on renal physiology -- and then extend that summer experience with an assigned mentor back home.

Why Digital Health Won't Be Replacing My Doctor

"I believe all digital health tools that can improve the experience for patients must be deployed. They have a role, they add value, they improve the experience, and they make the healthcare seeking process more dignified. But I’d be kidding if I expect these tools today to give me the insights and clinical acumen that Dr. JK brought to bear during our consultation."

First CRISPR Clinical Trial Receives Advisory Panel Approval

First CRISPR clinical trial could start by the end of this year.

Re-Energizing Nephrology: TPD Retreat 2016

The 2016 ASN Training Program Directors’ Retreat focused on new ways to re-energize the specialty and attract trainees to nephrology.

Nephrology Fellows' View

Dr. Lilia Maria Rizo Topete (Monterrey, Mexico) shares one of her memorable training experiences.

ASN Names Next Editor-in-Chief of CJASN

ASN has named Rajnish Mehrotra, MD, FASN, as CJASN Editor-in-Chief effective January 1, 2017. He will serve a six-year term.

Communities at ASN

ASN Communities offer multiple opportunities to connect with colleagues working in the areas that interest you most. Check out this rapidly growing and dynamic ASN initiative here.

High Fructose Corn Syrup May Be More Toxic than Table Sugar

In mice that were fed sugar in doses proportional to what many people eat, a fructose-glucose mixture found in high-fructose corn syrup was more toxic than sucrose or table sugar in females, increasing their death rates by 1.9-times and reducing their reproductive capacity by 26%. No differences were seen in males. Both high-fructose corn syrup and table sugar contain roughly equal amounts of fructose and glucose, but they exist as separate molecules, or monosaccharides, in corn syrup. In sucrose or table sugar, they exist as a disaccharide compound.

Genetic Markers in Mice and Humans Linked with Obesity

By analyzing epigenetic markers, or chemical tags, at more than 7 million sites in the DNA of the fat cells in mice, researchers found clear differences between normal and obese mice—and they found a similar pattern in human cells. Some of the epigenetic changes associated with obesity affect genes already known to raise diabetes risk. Others affect genes that had not been conclusively linked to the disease, but that have roles in metabolism. Some of the genes regulate insulin action on sugar uptake, making them potential targets for treating type 2 diabetes.