Filtration Markers May Predict ESRD and Mortality Risks

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Concentrations of four markers of filtration, individually and in combination, are consistently associated with the risk of progression to end stage renal disease (ESRD), reports a study in the American Journal of Kidney Diseases.

Members of the Chronic Kidney Disease Biomarkers Consortium analyzed filtration markers and their association with 1-year change in measured (mGFR) and estimated (eGFR) glomerular filtration rate. The study included observational data on 317 patients from the Modification of Diet in Renal Disease study and 373 patients from the African American Study of Kidney Disease and Hypertension (AASK).

At 12- and 24-month follow-up visits, patients