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Biomarkers in Acute Kidney Injury and Beyond

  • 1 Justin Lee Loy, MD, is a fellow at the University of Florida, Gainsville. Joseph Mattana, MD, is chair of medicine at St. Vincent’s Medical Center in Bridgeport, CT.
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At present, the renal community suffers from a limited array of noninvasive tools in routine clinical use that can accurately and rapidly identify acute kidney injury (AKI) and generate useful prognostic information to help guide current therapy and anticipate major subsequent events, some of which may require substantial interventions, such as initiating renal replacement therapy.

Similar to cardiology and the use of troponins in acute myocardial infarction, there is an urgent need for new biomarkers to help guide the treatment of patients with renal disease. The study of biomarker applications in renal disease continues to cover a broad spectrum of

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