Early diabetic kidney disease (DKD)—often clinically expressed as proteinuria—is associated with a 16-year reduction in life expectancy, reports a study from Taiwan in Kidney International.
The prospective cohort study included 512,700 adults participating in a comprehensive health surveillance study between 1994 and 2008. Of these, 9067 patients had early DKD, defined as stage 1 to 3 chronic kidney disease (CKD) based on estimated glomerular filtration rate and/or albuminuria. Another 50,977 patients had early CKD without diabetes and 18,388 had diabetes without CKD. Life expectancy was compared among groups and with the reference group of individuals who had neither