Confounders Obscure Link between Preeclampsia and ESRD

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The roles of obesity and pre-existing kidney disease make it difficult to assess the true nature of the association between preeclampsia and end stage renal disease (ESRD), concludes a report in the American Journal of Kidney Diseases.

The researchers used the US Renal Data System to identify 34,581 women who gave birth in Olmsted County, Minn., between 1976 and 2010. Forty-four women with confirmed ESRD were matched for year of birth, age at first pregnancy, and parity to two controls. In the cases, median time from last pregnancy to ESRD onset was 17.7 years.

Pregnancies affected by preeclampsia