• Yanik EL, et al.. Cancer risk after pediatric solid organ transplantation. Pediatrics 2017; 139: e20163893.

Some Pediatric Transplant Patients May Have a Markedly Increased Cancer Risk

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Children who have received solid organ transplants are at high risk of cancer, particularly non-Hodgkin’s lymphoma, according to a study in Pediatrics.

In the US Transplant Cancer Match study, data from the Scientific Registry of Transplant Recipients were linked to 16 state and regional cancer registries. Of approximately 40,500 solid organ transplants performed between 1987 and 2011 in patients younger than 18 years, 45% were in a region covered by one of the linked cancer registries.

Counts of registry-observed cancers were divided by the counts that were to be expected from general population rates in order to calculate standardized incidence