Early Conversion to Belatacept: A Case-Control Study

Restricted access

In kidney transplant recipients with low kidney function, early conversion from tacrolimus- to belatacept-based immunosuppression leads to a small but significant increase in estimated glomerular filtration rate (GFR), reports a study in Transplantation.

The retrospective study included two groups of 30 matched transplant recipients with low but stable eGFR: typically less than less than 40 mL/min/m2 (median 23 mL/min/m2. From 2012 to 2016, the study center had a protocol to convert patients with low kidney function at least 1 month posttransplant from tacrolimus to belatacept. Cases were matched on a wide range of variables