Serum suPAR Said to Predict Pediatric Kidney Disease Progression

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Higher serum soluble urokinase receptor (suPAR) levels are associated with a higher risk of CKD progression in children, according to a study in JAMA Pediatrics.

The findings are the latest to suggest suPAR may be a useful biomarker for predicting onset or progression of kidney disease. A 2015 study in the New England Journal of Medicine showed that elevated levels of suPAR are linked with the incidence of CKD and faster decline of renal function in adult patients (Hayek SS, et al. N Engl J Med 2015; 373:1916–1925).

Not having good early biomarkers can