Renal Cancer Drugs Show Similar Survival Rates

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A phase three trial showed that an already approved drug, sorafenib (Nexavar, manufactured by Bayer Pharma), and tivozanib share a similar survival period for patients with advanced renal cell cancer.

Sorafenib, also used for liver cancer, is a treatment for advanced renal cell cancer, and patients use it after earlier treatments with interferon-α or interleukin-2 have failed or if physicians deem these treatments inadequate. Sorafenib is a multikinase inhibitor (a tyrosine kinase inhibitor, an angiogenesis inhibitor, and a vascular endothelial growth factor [VEGF] inhibitor).

Tivozanib, the study drug, is a selective inhibitor of all three VEGF receptors that was designed