Groenwald HF , Januzzi JL , Damman K , et al.. Anemia and mortality in heart failure patients: a systematic review and meta–analysis. J Am Coll Cardiol 2008; 52:818–827.
He S-W , Wang L-X . The impact of anemia on the prognosis of chronic heart failure: a meta-analysis and systemic review. Congest Heart Fail 2009; 15:123–130.
Anand IS . Anemia and chronic heart failure. J Am Coll Cardiol 2008; 52:501–511.
Silverberg DS , Wexler D , Iaina A , et al.. The correction of anemia in patients with the combination of chronic kidney disease and congestive heart failure may prevent progression of both conditions. Clin Exp Nephrol 2009; 13:101–106.
Boerrigter G , Costello-Boerrigter LC , Abraham WT , et al.. Cardiac resynchronization therapy improves renal function in human heart failure with reduced glomerular function. J Card Fail 2008; 14:539–546.
Weiss G . Iron metabolism in the anemia of chronic disease. Biochim Biophys Acta 2009; 1790:682–693.
Weiss G , Meusburger E , Radacher G , et al.. Effect of iron treatment on circulating cytokine levels in ESRD patients receiving recombinant human erythropoietin. Kidney Int 2003; 64:572–578.
Vlahakos DV , Marathias KP , Madias NE . The role of the renin angiotensin system in the regulation of erythropoiesis. Am J Kidney Dis 2010;
Abramov D , Cohen RS , Katz SD , et al.. Comparison of blood volume characteristics in anemic patients with low versus preserved left ventricular ejection fraction. Am J Cardiol 102:1069–1072.
Ngo K , Kotecha D , Walters JA , et al.. Erythropoiesis-stimulating agents for anaemia in chronic heart failure patients. Cochrane Database Syst Rev 2010; Jan 20;(1):CD007613.
Ponikowski P , Anker SD , Szachniewicz J , et al.. Effect of darbepoetin alpha on exercise tolerance in anemic patients with symptomatic chronic heart failure. J Am Coll Cardiol 2007; 49:753–762.
Van Veldhuisen DJ , Dickstein K , Cohen-Solal A , et al.. Randomized, double-blind, placebo-controlled study to evaluate the effect of two dosing regimens of darbepoetin alfa in patients with heart failure and anaemia. Eur Heart J 2007; 28:2208–2216.
Ghali J , Anand I , Abraham WT , et al.. Randomized double blind trial of darbepoetin alpha treatment in patients with symptomatic heart failure and anemia. Circulation 2008; 117:526–535.
Klapholz M , Abraham WT , Ghali JK , et al.. The safety and tolerability of darbepoetin alfa in patients with and symptomatic heart failure. Eur J Heart Fail 2009; 11:1071–1077.
Abraham WT , Anand IS , Klapholz M , et al.. Treatment of anemia with darbepoetin alfa in heart failure. Congest Heart Fail 2010; 16:87–95.
Arcasoy MO . The non-haematopoietic biological effects of erythropoietin. Br J Haematol 2008; 141:14–31.
Naito Y , Tsujino T , Matsumoto M , et al.. Adaptive response of the heart to long term anemia induced by iron deficiency. Am J Physiol Heart Circ Physiol 2009; 296:H585–593.
Dong F , Zhang X , Culver B , et al.. Dietary iron deficiency induces ventricular dilation, mitochondrial ultrastructural aberrations and cytochrome C release: involvement of nitric oxide synthase and protein tyrosine nitration. Clin Sci 2005; 109:277–286.
Murphy CL , Fitzimmons RJ , Jardine AJ , et al.. Routine assessment of iron status in all patients with heart failure may identify those at risk of developing anemia. Eur J Heart Fail 2007; 61:103.
Grzeslo, Jankowska EA , Witkowski J et al.. Iron deficiency is a common finding in patients with stable chronic heart failure. Eur J Heart Fail (suppl) 2006; 5:132.
De Silva R , Rigby AS , Klaus KA , et al.. Anemia, renal dysfunction, and their interaction in patients with chronic heart failure. Am J Cardiol 2006; 98:391–398.
Opasich C , Cazzola M , Scelsi L , et al.. Blunted erythropoietin production and defective iron supply for erythropoiesis as major causes of in patients with chronic heart failure. Eur Heart J 2005; 26:2232–2237.
Nanas JN , Matsouka C , Karageorgopoulos D , et al.. Etiology of anemia in patients with advanced heart failure. J Am Coll Cardiol 2006; 48:2485–2489.
Bolger AP , Bartlett FP , Penston HS , et al.. Intravenous iron alone for the treatment of anemia in patients with chronic heart failure. J Am Coll Cardiol 2006; 48:1225–1227.
Usmanov RI , Zueva EB , Silverberg DS , et al.. Intravenous iron without erythropoietin for the treatment of iron deficiency anemia in patients with moderate to severe congestive heart failure and chronic renal insufficiency. J Nephrol 2006; 21:236–242.
Toblli J , Lombrana A , Duarte P , et al.. Intravenous iron reduces NT- pro-BNP in anemic patients with chronic heart failure and renal insufficiency. J Am Coll Cardiol 2007; 50:1657–1665.
Okonko DO , Grzeslo A , Witkowski T , et al.. Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency. J Am Coll Cardiol 2008; 51:103–112.
Anker SD , Comin Colet J , Fillipatos G , et al.. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med 2009; 361:2436–2448.
Rozen-Zvi B , Gafter-Gvili A , Paul M , et al.. Intravenous versus oral iron supplementation for the treatment of anemia in CKD: systematic review and meta-analysis. Am J Kidney Dis 2008; 52:897–906.
McMurray JJV , Anand IS , Diaz R , et al.. Design of the reduction of events with darbepoetin alfa in Heart Failure (RED-HF): a phase III, anemia correction morbidity-mortality trial. Eur J Heart Fail 2009; 11:795–801.