GLP1ra orforglipron and injectable triple agonist retatrutide
Wharton S, et al.; GZGI Investigators. Daily oral GLP-1 receptor agonist orforglipron for adults with obesity. N Engl J Med (published online ahead of print June 23, 2023). doi: 10.1056/NEJMoa2302392; https://www.nejm.org/doi/10.1056/NEJMoa2302392
Jastreboff AM, et al.; Retatrutide Phase 2 Obesity Trial Investigators. Triple-hormone-receptor agonist retatrutide for obesity—a phase 2 trial. N Engl J Med 2023; 389: 514–526. doi: 10.1056/NEJMoa2301972
Knop FK, et al.; OASIS 1 Investigators. Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): A randomised, double-blind, placebo-controlled, phase 3 trial. Lancet (published online ahead of print June 23, 2023). doi: 10.1016/S0140-6736(23)01185-6; https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01185-6/fulltext
Perkovic V, et al. FC 123: Baseline characteristics of the Flow trial population: Kidney outcomes trial with once-weekly semaglutide in people with type 2 diabetes and chronic kidney disease. Nephrol Dial Transplant 2022; 37 (Suppl 3). https://academic.oup.com/ndt/article/37/Supplement_3/gfac126.002/6578114?login=true