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Exercise Therapy Enhances Exercise Capacity and Cardiorespiratory Fitness in Patients with CKD

  • 1 Patrick C. Ahearn, MD, MAS, and Xingxing S. Cheng, MD, MS, are Clinical Assistant Professors with the Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, CA.
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Chronic kidney disease (CKD) is associated with physical function decline and worsening comorbidity burden. A recent study published in the Journal of the American Society of Nephrology (1) reports findings from the LANDMARK III study, a years-long, longitudinal randomized study of a multi-disciplinary, clinic-based and lifestyle intervention for Australian patients with CKD stages 3a−4. The intensive intervention required a treatment team of nurse practitioners, exercise physiologists, dieticians, diabetes educators, psychologists, and nephrologists. Risk factors addressed included blood pressure, weight, and cardiorespiratory fitness. The 81 intervention-group patients attended 4 weeks of behavior and lifestyle intervention and 8

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