• Camilo Cortesi

  • Figure 1.

    The lung kidney axis: interaction of various deleterious effects as a result of AKI and ARDS

  • Figure 2.

    The vicious cycle of ARDS and AKI: conditions created by dysfunction of one system lead to worsening of the other.

  • 1.

    Bellani G, et al. Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA 2016; 315:788800. doi: 10.1001/jama.2016.0291

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 2.

    Darmon M, et al. Acute respiratory distress syndrome and risk of AKI among critically ill patients. Clin J Am Soc Nephrol 2014; 9:13471353. doi: 10.2215/CJN.08300813

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 3.

    ARDS Definition Task Force, et al. Acute respiratory distress syndrome: the Berlin definition. JAMA 2012; 307:25262533. doi: 10.1001/jama.2012.5669

  • 4.

    National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, et al. Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 2006; 354:25642575. doi: 10.1056/NEJMoa062200

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5.

    Grams ME, et al. Fluid balance, diuretic use, and mortality in acute kidney injury. Clin J Am Soc Nephrol 2011; 6:966973. doi: 10.2215/CJN.08781010

  • 6.

    Liu KD, et al. Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury. Crit Care Med 2007; 35:27552761. PMID: 18074478

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7.

    Acute Respiratory Distress Syndrome Network, et al. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342:13011308. doi: 10.1056/NEJM200005043421801

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8.

    Kuiper JW, et al. Mechanical ventilation and acute renal failure. Crit Care Med 2005; 33:14081415. doi: 10.1097/01.ccm.0000165808.30416.ef

  • 9.

    Hemlin M, et al. The effects of hypoxia and hypercapnia on renal and heart function, haemodynamics and plasma hormone levels in stable COPD patients. Clin Respir J 2007; 1:8090. doi: 10.1111/j.1752-699X.2007.00031.x

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10.

    Nardelli LM, et al. Effects of acute hypercapnia with and without acidosis on lung inflammation and apoptosis in experimental acute lung injury. Respir Physiol Neurobiol 2015; 205:16. doi: 10.1016/j.resp.2014.09.007

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11.

    Hotter G, et al. Low O2 and high CO2 in LLC-PK1 cells culture mimics renal ischemia-induced apoptosis. Lab Invest 2004; 84:213220. doi: 10.1038/labinvest.3700026

  • 12.

    Guérin C, et al. Prone positioning in severe acute respiratory distress syndrome. N Engl J Med 2013; 368:21592168. doi: 10.1056/NEJMoa1214103

  • 13.

    Papazian L, et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010; 363:11071116. doi: 10.1056/NEJMoa1005372

  • 14.

    Combes A, et al. Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. N Engl J Med 2018; 378:19651975. doi: 10.1056/NEJMoa1800385

  • 15.

    Gaudry S, et al. Timing of renal support and outcome of septic shock and acute respiratory distress syndrome: A post hoc analysis of the AKIKI randomized clinical trial. Am J Respir Crit Care Med 2018; 198:5866 doi: 10.1164/rccm.201706-1255OC.

    • PubMed
    • Search Google Scholar
    • Export Citation

Acute Respiratory Distress Syndrome from a Kidney Perspective

Camilo Cortesi Camilo Cortesi, MD, is with the Division of Nephrology, University of California San Francisco.

Search for other papers by Camilo Cortesi in
Current site
Google Scholar
PubMed
Close
Restricted access
Save