Kidney biopsies for research: safety and feasibility

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Additional kidney cores for research purposes can be successfully and safely obtained from 90% of diabetic patients undergoing clinically indicated kidney biopsy, according to a research letter in CJASN.

The authors report an interim analysis from the multicenter Transforming Research in Diabetic Nephropathy (TRIDENT) study, a longitudinal cohort study using direct analysis of kidney tissue to identify biomarkers and new therapeutic targets for diabetic kidney disease. The analysis included data on 176 patients enrolled in TRIDENT. All had clinical indications for kidney biopsy and consented to undergo collection of an additional biopsy core for the study.

Biopsy was performed