• 1.

    Weaver DJ, Mitsnefes M. Cardiovascular disease in children and adolescents with chronic kidney disease. Semin Nephrol 2018; 38:559569

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 2.

    Modi ZJ, et al. Risk of cardiovascular disease and mortality in young adults with end-stage kidney disease: An analysis of the US kidney data system. JAMA Cardiol 2019; 4:353362.

    • Crossref
    • Search Google Scholar
    • Export Citation

CARDIOVASCULAR DISEASE and the Kidney

  • 1 Mohammed Elsadany, MD, Yifeng Yang, MD, and Joseph Mattana, MD, are associated with St. Vincent’s Medical Center, Bridgeport, Connecticut, and the Quinnipiac University Frank H. Netter MD School of Medicine, North Haven, Connecticut. Sonali Gupta, MD, is associated with the University of Rochester, Rochester, New York.
Restricted access

It has been well known for many years that cardiovascular disease disproportionately affects patients with chronic kidney disease (CKD) and kidney failure, both through acceleration of atherogenesis as a consequence of reduced kidney function and through the various comorbidities with which our patients are frequently afflicted. Despite growing mechanistic insights into kidney–heart interactions, atherogenesis, cardiac hypertrophy, valvular heart disease, and other phenomena and into new therapies that are available, patients with kidney disease continue to experience an excessive burden of cardiovascular disease and events.

Cardiovascular disease, particularly coronary artery disease, is more often a condition of the older individual, but

Save