Higher Mortality in Kidney Transplant Recipients Versus Matched CKD Patients

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Beyond the first year, kidney transplant recipients (KTRs) have an excess risk of mortality, compared to matched chronic kidney disease (CKD) patients who do not undergo kidney transplantation, reports a preliminary study in Nephrology Dialysis Transplantation.

The analysis included patients from two French multicenter prospective cohorts: 340 KTRs and 605 nontransplant CKD patients. The groups were matched on a propensity score incorporating six outcome-dependent variables assessed at cohort enrollment, including estimated glomerular filtration rate (eGFR). Mean eGFR at inclusion was 42 and 41 mL/min/1.73 m2, respectively. All-cause mortality was compared between groups, with cardiovascular events as