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Proteinuria After AKI Predicts Kidney Disease Progression, Study Suggests

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For hospitalized patients with acute kidney injury (AKI), postdischarge measurement of albuminuria may improve the ability to identify patients at higher subsequent risk of progressive kidney disease, according to a prospective, multicenter cohort study reported in the March issue of JAMA Internal Medicine.

Patients with an episode of AKI are at high risk of rapidly declining kidney function. New approaches are needed to identify those patients at highest risk of kidney disease progression.

Doubling of the urine albumin-to-creatine ratio (UACR) after hospital discharge is associated with a 1.5-fold increase in the odds of kidney disease progression, according to

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