• Figure 1.

    Facilitating cells interact with the HSC through numerous mechanisms to promote chimerism and tolerance

  • Figure 2.

    Algorithm for the non-myeloblative conditioning of the transplant recipient before and after the kidney transplant

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    Kawai T , et al. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 2013; 368:18501852.

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    Leventhal JR , Ildstad ST . Tolerance induction in HLA disparate living donor kidney transplantation by facilitating cell-enriched donor stem cell infusion: The importance of durable chimerism. Hum Immunol 2018; 79:272276.

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“Freedom” from Immunosuppression in Solid Organ Transplantation

Uday Nori Uday Nori, MD, is associate professor of medicine and program director of the nephrology fellowship program at The Ohio State University Wexner Medical Center, Columbus, OH, and is a member of the Kidney News Editorial Board.

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