New Directions in Diabetic Kidney Disease Trials

  • 1 Vlado Perkovic, MBBS, PhD, is Executive Director of The George Institute, Australia, Professor of Medicine at UNSW Sydney, and a staff specialist in nephrology at the Royal North Shore Hospital.
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The outlook for people diagnosed with type 2 diabetes and chronic kidney disease today is more hopeful than it has ever been. A broad array of treatments are available, and the last decade has seen an explosion of evidence from high-quality, properly powered, randomized trials that have defined the benefits and risks of many of these treatment options.

The 2008 decision by the U.S. Food and Drug Administration (FDA) and other regulatory agencies to require the conduct of cardiovascular safety trials for all new diabetes medications (1) has directly led to the generation of evidence that can guide

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