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Volume/Issue:
Volume 11: Issue 5
Page:
5–6
Publication Date:
01 May 2019
Online Publication Date:
06 May 2019
  • Figure 1.
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    Figure 1.

    Hemoglobin trends among dialysis patients in the United States from 2010 to 2017, New York

  • Figure 2.
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    Figure 2.

    Timeline of drug development of erythropoietin (EPO) analogues

Figure 1.

Hemoglobin trends among dialysis patients in the United States from 2010 to 2017, New York
Figure 2.

Timeline of drug development of erythropoietin (EPO) analogues
  • 1.

    Unger EF , et al. Erythropoiesis-stimulating agents: Time for a reevaluation. N Engl J Med 2010; 362:189–192.

  • 2.

    Lin FK , et al. Cloning and expression of the human erythropoietin gene. Proc Natl Acad Sci USA 1985; 82:7580–7584.

  • 3.

    Szczech LA , et al. Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomes. Kidney Int 2008; 74:791–798.

  • 4.

    Haase VH . Therapeutic targeting of the HIF oxygen-sensing pathway: Lessons learned from clinical studies. Exp Cell Res 2017; 356:160–165.

  • 5.

    Fishbane S , Frei GL , Maesaka J . Reduction in recombinant human erythropoietin doses by the use of chronic intravenous iron supplementation. Am J Kidney Dis 1995; 26:41–46.

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  • 6.

    Macdougall IC , et al. Intravenous iron in patients undergoing maintenance hemodialysis. N Engl J Med 2019; 380:447–458.

  • 7.

    Anker SD , et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med 2009; 361:2436–2448.

Editorial Type:
Features

Anemia and Chronic Kidney Disease: WHERE WE’VE BEEN, WHERE WE’RE GOING

Steven Fishbane Steven Fishbane, MD, is professor of medicine, division of nephrology, department of medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York.

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Volume/Issue:
Volume 11: Issue 5
Publication Date:
01 May 2019
Page:
5–6
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