The risks of cardiovascular events and mortality are lowest with the combination of moderate sodium intake and higher potassium intake, concludes an international prospective cohort study in the British Medical Journal.
The “Prospective Urban Rural Epidemiology” (PURE) study enrolled more than 103,000 adults, aged 35 to 70, from 628 urban and rural communities in low-, middle-, and high-income countries. Twenty-four-hour urinary sodium and potassium excretion were estimated (as surrogates for intake) from morning fasting urine samples.
During a median follow-up of 8 years, 6.1% of patients died or experienced a cardiovascular event. Risks of these outcomes were assessed