Kidney transplantation reduces mortality, mainly due to cardiovascular disease and infection, in patients with lupus nephritis, reports a study in Annals of Internal Medicine.
Through the United States Renal Data System, the researchers identified 20,974 individuals with kidney failure due to lupus nephritis (ESRD-LN) between 1995 and 2014. Of 9659 waitlisted patients, 5738 (59%) received a kidney transplant. Eighty-two percent of waitlisted patients were women and 60% were nonwhite.
Analyzed as a time-varying exposure, renal transplantation was associated with lower all-cause mortality among waitlisted patients: adjusted hazard ratio (HR) 0.30. There were also significant reductions in mortality due