Dozens of volatile organic compounds (VOCs) are found at elevated concentrations in expired gas from critically ill patients with acute kidney injury (AKI), reports a study in Critical Care Medicine.
The study included 20 mechanically ventilated patients with AKI, along with a control group of critically ill patients without AKI. The mechanically ventilated patients also had indications for dialysis.
Intensities of VOCs in breath samples were measured using multicapillary column ion-mobility spectrometry. Each patient’s “exhalome” was evaluated from 30 minutes before they started continuous venovenous hemodialysis through 7 hours after the start of dialysis.