Cover Kidney News
Volume/Issue:
Volume 11: Issue 3
Page:
15
Publication Date:
01 Mar 2019
Online Publication Date:
05 Mar 2019
  • Figure 1.
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    Figure 1.

    Concept of indirect allorecognition of polymorphic proteins (nonsynonymous SNPs, upper panel) and “loss of function” (homozygous knockout) variant mismatches (lower panel) between donors and recipients

Figure 1.

Concept of indirect allorecognition of polymorphic proteins (nonsynonymous SNPs, upper panel) and “loss of function” (homozygous knockout) variant mismatches (lower panel) between donors and recipients
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    Lachmann N, et al.. Donor-recipient matching based on predicted indirectly recognizable HLA epitopes independently predicts the incidence of de novo donor-specific HLA antibodies following renal transplantation. Am J Transplant 2017; 17:3076–3086.

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    Opelz G, et al.. Non-HLA transplantation immunity revealed by lymphocytotoxic antibodies. Lancet 2005; 365:1570–1576.

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    MacArthur DG, et al.. A systematic survey of loss-of-function variants in human protein-coding genes. Science 2012; 335: 823–828.

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    International Genetics & Translational Research in Transplantation Network. Design and Implementation of the International Genetics and Translational Research in Transplantation Network. Transplantation 2015; 99:2401–2412.

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    Reindl-Schwaighofer R, et al.. Genome-wide non-HLA incompatibility between donor and recipient contributes to kidney allograft attrition [Abstract]. JASN 2018; abs: #1802.

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    DeWolf S, et al.. Quantifying size and diversity of the human T cell alloresponse. JCI Insight 2018, in press.

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    Glanville J, et al.. Identifying specificity groups in the T cell receptor repertoire. Nature 2017; 547:94–98.

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    Dash P, et al.. Quantifiable predictive features define epitope-specific T cell receptor repertoires. Nature 2017; 547:89–93.

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    Reindl-Schwaighofer R, et al.. Mechanisms underlying human genetic diversity: consequence for antigraft antibody responses. Transpl Int 2018; 31:239–250.

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PERSONALIZED RENAL TRANSPLANTATION: A View from the EU 28+ Countries

Roman Reindl-Schwaighofer Roman Reindl-Schwaighofer, Andreas Heinzel, and Rainer Oberbauer are associated with the Medical University of Vienna, Austria.

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Andreas Heinzel Roman Reindl-Schwaighofer, Andreas Heinzel, and Rainer Oberbauer are associated with the Medical University of Vienna, Austria.

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Rainer Oberbauer Roman Reindl-Schwaighofer, Andreas Heinzel, and Rainer Oberbauer are associated with the Medical University of Vienna, Austria.

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Volume/Issue:
Volume 11: Issue 3
Publication Date:
01 Mar 2019
Page:
15
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