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Volume/Issue:
Volume 11: Issue 3
Page:
13
Publication Date:
01 Mar 2019
Online Publication Date:
05 Mar 2019
  • Figure 1.
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    Figure 1.

    Restricted cubic spline plot of the association between change in eGFR and urinary concentrations of Dickkopf-3 (DKK) and creatinine during the early treatment phase in participants of the STOP-IgAN trial

Figure 1.

Restricted cubic spline plot of the association between change in eGFR and urinary concentrations of Dickkopf-3 (DKK) and creatinine during the early treatment phase in participants of the STOP-IgAN trial
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    Levin A, et al.. Global kidney health 2017 and beyond: A roadmap for closing gaps in care, research, and policy. Lancet 2017; 390:1888–1917.

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    KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int 2013; [Suppl 3]:1–150.

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    Coresh J, et al.. Decline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality. JAMA 2014; 311:2518–2531.

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    Tangri N, et al.. Multinational assessment of accuracy of equations for predicting risk of kidney failure: A meta-analysis. JAMA 2016; 315:164–174.

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    Porrini E, et al.. Non-proteinuric pathways in loss of renal function in patients with type 2 diabetes. Lancet Diab Endocrinol 2015; 3:382–391.

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    Federico G, et al.. Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis. J Clin Invest Insight 2016; 1:e84916.

  • 7.

    Zewinger S, et al.. Dickkopf-3 (DKK3) in urine identifies patients with short-term risk of eGFR loss. J Am Soc Nephrol 2018; 29:2722–2733.

  • 8.

    Rauen T, et al.. Intensive supportive care plus immunosuppression in IgA nephropathy. N Engl J Med 2015; 373:2225–2236.

Editorial Type:
Features

Identifying Patients at High Risk for Short-Term Chronic Kidney Disease Progression: Still a Challenge?

Danilo Fliser Danilo Fliser, MD, is associated with the Department of Internal Medicine IV, Saarland University Medical Center, Homburg/Saar, Germany.

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Volume/Issue:
Volume 11: Issue 3
Publication Date:
01 Mar 2019
Page:
13
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