High Risk of Vaccine Preventable Infections in Kids with Organ Transplants

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Pediatric organ transplant recipients are at greatly increased risk of hospitalization for vaccine-preventable infections (VPIs), reports a study in JAMA Pediatrics.

The retrospective study included 6980 patients who were less than 18 years old (mean 6.2 years) when they underwent a solid organ transplant from 2004 through 2011. Transplants were performed at 45 not-for-profit US children’s hospitals participating in the Pediatric Health Information System database. There were 2,583 kidney transplant recipients, comprising 37.0% of the sample.

Numbers of hospitalizations for VPIs in the 5 years after transplantation were analyzed, based on diagnostic codes. The morbidity, mortality, and costs