Higher UACR Linked to Cardiovascular Risk in Diabetes

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Urinary albumin excretion is independently associated with a range of adverse cardiovascular outcomes in patients with type 2 diabetes, reports a study in JAMA Cardiology.

The study included data on 15,760 patients from the SAVOR-TIMI 53 study: a randomized, placebo-controlled trial of the oral hypoglycemic drug saxagliptin in patients with type 2 diabetes at high cardiovascular risk. Two-thirds of patients were men. Baseline urinary albumin to creatinine ratio (UACR) was less than 10 mg/g in 36.8% of patients, 10 to 30 mg/g in 24.7%, 30 to 300 mg/g in 28.1%, and greater than 300 mg/g in 10.4%.

At a

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