Longer Time on Dialysis Linked to Increased Transplant Failure

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For non-preemptive living donor kidney transplant recipients, longer pretransplant dialysis exposure is associated with a higher risk of allograft failure, reports a study in the American Journal of Kidney Diseases.

The retrospective study included 77,607 adult, first-time, kidney-only living donor transplant recipients reported to the Scientific Registry of Transplant Recipients between 2000 and 2016. Of these, 51,390 underwent non-preemptive transplantation. Duration of pretransplant dialysis exposure was examined for association with kidney transplant failure from any cause including death. Median duration of dialysis exposure in the non-preemptive transplant group was 14 months.

Patients with longer pretransplant dialysis exposure were