Elevated blood urea nitrogen (BUN) levels are associated with an increased risk of developing diabetes, according to a study in Kidney International.
The researchers analyzed a national cohort of more than 1.3 million US veterans enrolled in the VA Health Care System. All patients were initially free of diabetes. At the time of cohort entry, 8.77% of individuals had an elevated BUN level of greater than 25 mg/dL. Risk of incident diabetes associated with BUN was assessed over a median follow-up of nearly 5 years, including joint risk models of estimated glomerular filtration rate (eGFR) and BUN.