Immune Checkpoint Inhibitors for Cancer Treatment Have Renal Side Effects

Restricted access

Courtesy Ala Abudayyeh

Immunotherapy has successfully treated several recalcitrant forms of cancers and is on the cusp of revolutionizing treatment. But as with any new therapy, greater use is revealing side effects that must be managed, including dangers to the kidney.

Nephrologists need to be aware of these potential problems and the ways to counter them, according to Kenar D. Jhaveri, MD, professor of medicine in the division of kidney diseases and hypertension at Hofstra Northwell School of Medicine in Great Neck, N.Y. The most common of these problems are immune-mediated, including acute interstitial nephritis (AIN) and glomerular diseases, both