Risk Equation Predicts Outcomes in Pediatric CKD

Restricted access

In children with chronic kidney disease (CKD), the kidney failure risk equation (KFRE) performs well in predicting the risk of progression to end stage renal disease (ESRD), concludes a study in JAMA Pediatrics.

The retrospective analysis included 603 children from a multicenter pediatric CKD cohort study. About 63% of the patients were boys. Their median age at study entry was 12 years and they had a median estimated glomerular filtration rate (eGFR) of 44 mL/min/1.73 m2. Two versions of the KFRE were analyzed for their ability to predict progression to ESRD: a four-variable version (age, sex,