Findings

For patients with nondiabetic chronic kidney disease (CKD), urinary sodium excretion rate is not associated with the long-term risk of kidney failure, reports a study in Kidney International.

Recent increases in obstetric acute renal failure are limited to women with hypertensive disorders of pregnancy, suggests a report in the British Medical Journal.

Older adults taking atypical antipsychotic drugs may be at increased risk of acute kidney injury (AKI), reports a study in the Annals of Internal Medicine.

A new product combining an angiotensin-receptor blocker (ARB) and a neprilysin inhibitor lowers mortality and hospitalization rates in patients with heart failure, compared with enalapril, concludes a trial in the New England Journal of Medicine.

Many patients meeting the traditional criteria for “early care” for chronic kidney disease (CKD) do not receive adequate care just before renal replacement therapy (RRT) is begun, according to a study in Kidney International.

In patients with CKD, strict BP control—leading to a treated systolic BP (SBP) below 120 mm Hg—is associated with increased all-cause mortality, reports a study in JAMA Internal Medicine.

The vascular changes of antiphospholipid syndrome nephropathy involve activation of the mammalian target of rapamycin complex (mTORC) pathway, suggesting a potential benefit of sirolimus after kidney transplantation, according to a study in the New England Journal of Medicine.

Living kidney donors in the United States sometimes have trouble buying or changing life and health insurance policies, reports a study in the American Journal of Transplantation.

The survey study included 1046 individuals who underwent live donor nephrectomy at one transplant center in the United States between 1970 and 2011. Donors were asked whether they had initiated or changed their health or life insurance after donating and whether they had any difficulties in doing so.

Nonalcoholic fatty liver disease (NAFLD), in terms of both presence and severity, is an independent risk factor for CKD, concludes a meta-analysis in PLOS Medicine.

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