Multilevel, multicomponent strategies provide the greatest reductions in blood pressure (BP) for patients with hypertension, concludes a meta-analysis in Annals of Internal Medicine.

In children with chronic kidney disease (CKD), the kidney failure risk equation (KFRE) performs well in predicting the risk of progression to end stage renal disease (ESRD), concludes a study in JAMA Pediatrics.

For undocumented immigrants with end stage renal disease (ESRD), standard dialysis three times weekly reduces mortality and hospital days, compared to emergency-only dialysis, reports a study in The Journal of the American Medical Association.

A salivary urea nitrogen (SUN) dipstick test is specific—but not sensitive—for diagnosis of obstetric-related acute kidney injury (AKI) in high-risk Malawian women, reports a study in the open-access journal Kidney International Reports.

For general surgery patients in the surgical ICU, the chances of survival to discharge decrease with each day of continuous renal replacement therapy (CRRT), according to a study in JAMA Surgery.

Very long-term follow-up suggests a twofold increase in chronic kidney disease (CKD) risk among black women with pregnancies affected by gestational diabetes mellitus, reports a study in American Journal of Kidney Diseases.

In kidney transplant recipients with low kidney function, early conversion from tacrolimus- to belatacept-based immunosuppression leads to a small but significant increase in estimated glomerular filtration rate (GFR), reports a study in Transplantation.

Anti-inflammatory therapy with canakinumab—targeting the interleukin-1β (IL-1β) innate immunity pathway—reduces cardiovascular events in patients with previous myocardial infarction (MI), reports a trial in The New England Journal of Medicine.

Chronic hepatitis C virus (HCV) infection is associated with an increased risk of chronic kidney disease (CKD), with the extent of risk depending on viral load and genotype, reports a study in Kidney International.